The making of an epidemiologist: John Snow before the Broad Street pump
(Communicable
Disease and Public Health, December 2002; 5(4): 265-348)
Reproduced with permission of the The Health Protection Agency, Communicable Disease Surveillance Centre © HPA
Dr R Stanwell-Smith
Honorary Secretary, The John Snow Society
In 1831 a young surgical apprentice in Newcastle "wilfully disturbed the congregation" at a religious meeting by letting off a firecracker1. This 17 year old firebrand became the punctilious, but still at times pugnacious, Dr John Snow (1813-1858), who made such brilliant contributions to epidemiology and to anaesthesia, that he is claimed as the father of both. A search on the Internet now produces 70 or more pages of sites mentioning Dr John Snow, mostly in relation to epidemiology2. Eponymous lectures, societies, organisations and buildings reflect his iconic status and Snow's influence extends from medicine to mapping, with water science and sanitation also staking a claim. Most students of epidemiology are familiar with the story of the Broad Street pump and its investigation by Snow during the cholera epidemic in London's Soho in 1854. Many are also aware that at the time of this epidemic, Snow was also an established physician with a large anaesthetic practice, including the first anaesthetic given at a royal birth. Few know anything about the early years that shaped this extraordinary man. Now, Dr Spence Galbraith has written the definitive account of Snow's life before the Broad Street pump1. Dr Galbraith, the first Director of the Communicable Disease Surveillance Centre, was inspired by Snow's work to take up a career in public health and epidemiology. He gave one of the early 'Pump Handle Lectures' for the John Snow Society in 1994 and the book is the result of his further research into Snow's early life, incidentally correcting several of the inaccuracies recorded by Snow's first biographer, Richardson2 and perpetuated or compounded since Richardson in other accounts of Snow.
What do these new insights into Snow's development tell us about how to be a good communicable disease epidemiologist? The firecracker episode was uncharacteristic of Snow's later, apparently exemplary behaviour, but it also indicates, possibly, an early sign of later rebelliousness against received knowledge and norms of the day. During one of his assistantships, his behaviour shocked the apothecary and his family, the former through burning the old bandages (the apothecary's custom was to re-use them); and the latter through his strict vegetarian diet and views on temperance. Although this was an era of rapid change in medical practice, with the introduction of new instruments such as the stethoscope, and regularisation of routes to qualification, the apothecary in question was unqualified.
Snow, by contrast, chose to take the available examinations of the day and to ensure that he gained wide clinical experience as well as respected qualifications, and this was a step that gave more authority to his later controversial views. One of the most fascinating aspects of Dr Galbraith's account of these early years is the vivid impression of an evolving and forward looking medical school at Newcastle in the 1820s and of general practice in the 1830s. Snow also benefited from a childhood and schooling in York, which was one of the most important cities of the time, undergoing major changes in trade, building and social structures. He grew up surrounded by change, and perhaps this made him more confident in embracing the changes in ideas and practice that characterised his later career. He took full advantage of the 'natural experiments' all around him, including the cholera epidemic of 1831-2 in Newcastle, keeping careful records of his observations. It was essential experience for studying the "grand experiment"4 of the changes in water supply that informed his theory of the transmission of cholera. His case books5 of his practice in London demonstrate his attention to clinical detail and excellent record keeping: another example of what is required of a good epidemiologist. Snow's brilliant work on cholera shows how he drew on this accumulated experience, for example in writing of how cholera spread amongst children6:
" when it is remembered that children get their hands into everything, and are constantly putting their fingers in their mouths, it is not surprising that the malady spread in this manner"
What seems obvious to us now was highly controversial in the science of the 1840s and 1850s, dominated by miasmic theories of disease transmission. From Snow's early experiences and training we see that he did not emerge, icon-like, when he chanced upon the outbreak surrounding the pump in Broad Street. Instead, the combination of his medical training, scientific experiments and application of logic to his observations all led him to the point when he could make well informed deductions: this predating our current emphasis on evidence bases by a century and a half.
Epidemiology and public health have undergone many changes since his time, but Dr Galbraith's researches on Snow's early years lend weight to the idea that Snow exemplified the ideal public health epidemiologist: determined, dedicated and highly skilled. He made progress by being difficult7,8, unafraid to challenge the views of other physicians and scientists, presenting and demanding evidence in turn. He also appeared to recognise the advantages of multidisciplinary public health, in working with non-medical colleagues to undertake investigations and to ensure that research was followed by action. Snow also showed political skills - another pre-requisite for achievement in public health - by joining and enthusiastically supporting several medical societies, and becoming a founder member of the council of the Epidemiological Society of London1. Above all, the early years of Snow's life show that clinical experience and clinical observation were fundamental to his later achievements: this must inform any debate of the role of clinicians in epidemiology and in public health. Snow would no doubt have wondered why the matter needed debate, but we can be sure that he would have presented cogent arguments.
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